Directors' Holdings

Prof. Dr. Horst Domdey, Chairman of Supervisory Board 39,125 0
Dr. Yita Lee00
Antoinette Hiebeler-Hasner00
Dr. Keith Manchester00
Ronald Scott00
Dr. Gerd Zettlmeissl00
Total Supervisory Board39,125 0
Prof. Dr. Dolores J. Schendel, Chief Scientific Officer 1) 829,11832,500
Dr. Thomas Taapken3,0000
Dave Lemus040,000
Total Executive Board 832,11872,500
1) Prof. Schendel indirectly holds 829,118 Medigene shares in her capacity as Managing Director of DJSMontana Holding GmbH. Of this total, 753,303 Medigene shares can be allocated to Prof. Schendel directly.