Directors' Holdings

Prof. Dr. Horst Domdey, Chairman of Supervisory Board 39,125 0
Dr. Yita Lee00
Antoinette Hiebeler-Hasner00
Dr. Keith Manchester1)00
Ronald Scott 00
Dr. Gerd Zettlmeissl 00
Dr. Frank Mathias2)20,197n.a.
Total Supervisory Board59,322136,089
Prof. Dr. Dolores J. Schendel, Chief Executive Officer and Chief Scientific Officer 3)846,29652,500
Dr. Thomas Taapken 4)020,000
Dr. Kai Pinkernell 5)033,438
Total Executive Board846,296105,938

1) Dr. Manchester is Managing Director and Head at Life Sciences QVT Financial LP. Funds managed by QVT held 1,072,879 shares in Medigene AG according to the last voting rights notification as of 08 June 2018.

2) Dr. Frank Mathias, Member of the Supervisory Board since 15 May 2018.

3) Prof. Dr. Schendel indirectly holds 846,296 Medigene shares in her capacity as Managing Director of DJS Montana Holding GmbH, which all are directly allocated to Prof. Dr. Schendel.

4) Dr. Thomas Taapken, Member of the Executive Board until 31 August 2018 (Chief Financial Officer)

5) Dr. Kai Pinkernell, Member of the Executive Board since 1 April 2018 (Chief Medical Officer & Chief Development Officer).